The Signaling Group - Major Publications

Brix DM, Rafn B, Bundgaard Clemmensen K, Andersen SH, Ambartsumian N, Jäättelä M, Kallunki T. Screening and identification of small molecule inhibitors of ErbB2-induced invasion. Mol Oncol 8, 1703-1718, 2014

Jaiswal J, Lauritzen S, Scheffer L, Sakaguchi M, Bunkenborg J, Simon S, Kallunki T, Jäättelä M, Nylandsted J. S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells. Nature Communications 5, 3795-3799, 2014

Brix DM, Clemmensen KK, Kallunki T. When Good Turns Bad: Regulation of Invasion and Metastasis by ErbB2 Receptor Tyrosine Kinase. Cells 3(1), 53-78, 2014

Kallunki T, Olsen OD, Jäättelä M. Cancer-associated lysosomal changes: friends or foes? Oncogene 32, 1995-2004, 2013

Rafn B, Kallunki T. A way to invade: A story of ErbB2 and lysosomes. Cell Cycle 11, 2415-2416, 2012

Rafn B, Nielsen CF, Andersen SH, Szyniarowski P, Corcelle-Termeau E, Valo E,  Fehrenbacher N, Olsen CJ, Daugaard M, Egebjerg C, Bøttzauw T, Kohonen P, Nylandsted J,  Hautaniemi S,  Moreira J, Jäättelä M, Kallunki T. ErbB2-driven breast cancer cell invasion depends on a complex signalling network activation myeloid zinc-finger-1-dependent cathepsin B expression. Mol Cell 45, 764-776, 2012

Mathiasen DP, Egebjerg C, Andersen SH, Rafn B, Puustinen P, Khanna A, Daugaard M, Valo E, Tuomela S, Bøttzauw T, Nielsen CF, Willumsen B, Hautaniemi S, Lahesmaa R, Westermarck J, Jäättelä M, Kallunki T. Identification of a c-Jun N-terminal kinase 2 dependent signal amplification cascade that regulates c-Myc levels in Ras transformation. Oncogene 31, 390-401, 2012

Szyniarowski P, Corcelle-Termeau E, Farkas T, Høyer-Hansen M, Nylandsted J, Kallunki T, Jäättelä M. A comprehensive siRNA screen for kinases that suppress macroautophagy in optimal growth conditions. Autophagy 7, 892-903, 2011

Westerlund N, Zdrojewska J, Padzik A, Komulainen E, Björkblom B, Rannikko E, Tararuk T, Garcia-Frigola C, Sandholm J, Nyguen L, Kallunki T, Courtney MJ, Coffey ET. SCG/stathmin-2 phosphorylation determines the duration of multipolar stage and migration speed. Nature Neurosci 14, 305-313, 2011